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| Calcium Channels, L-Type Dihydropyridine Receptors | L-Type Calcium Channels | L-Type VDCC alpha-1 Subunit | Long-Lasting Calcium Channels | Receptors, Dihydropyridine | Dihydropyridine Receptor | L-Type Calcium Channel | L-Type VDCC | L-Type VDCC alpha-2 Subunit Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites. |