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| Similar words: Abelson murine leukemia virus | |
| Abelson murine leukemia virus Abelson Leukemia Virus | Leukemia Virus, Abelson | Virus, Abelson Leukemia A replication-defective strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukemia after superinfection with FRIEND, MALONEY, or RAUSCHER MURINE LEUKEMIA VIRUS. | |
| Moloney murine leukemia virus Moloney Leukemia Virus | Leukemia Virus, Moloney | Virus, Moloney Leukemia A strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) arising during the propagation of S37 mouse sarcoma, and causing lymphoid leukemia in mice. It also infects rats and newborn hamsters. It is apparently transmitted to embryos in utero and to newborns through mother's milk. | |
| Fusion Proteins, bcr-abl Oncogene Protein p190(bcr-abl) | Oncogene Protein p210(bcr-abl) | bcr-abl Fusion Proteins | Fusion Proteins, bcr abl | Proteins, bcr-abl Fusion | bcr abl Fusion Proteins Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in Abelson murine leukemia virus. | |
| Rauscher Virus Virus, Rauscher A strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) associated with mouse tumors similar to those caused by the FRIEND MURINE LEUKEMIA VIRUS. | |
| Leukemia Virus, Murine Graffi Virus | Graffi' | s Chloroleukemic Strain | Murine leukemia virus | Leukemia Viruses, Murine | Mouse Leukemia Viruses | Murine Leukemia Viruses | Graffi Chloroleukemic Strain | Graffis Chloroleukemic Strain | Leukemia Viruses, Mouse Species of GAMMARETROVIRUS, containing many well-defined strains, producing leukemia in mice. Disease is commonly induced by injecting filtrates of propagable tumors into newborn mice. | |
| Gross Virus Virus, Gross A strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) obtained from inbred mice with a high incidence of spontaneous lymphoid leukemia. Infection is passed by vertical transmission from one generation to another through the ovum. | |
| Radiation Leukemia Virus RadLV | Leukemia Virus, Radiation | Leukemia Viruses, Radiation | Radiation Leukemia Viruses A strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) isolated from radiation-induced lymphomas in C57BL mice. It is leukemogenic, thymotrophic, can be transmitted vertically, and replicates only in vivo. | |
| Kirsten murine sarcoma virus Kirsten Sarcoma Virus | Sarcoma Virus, Kirsten | Virus, Kirsten Sarcoma A replication-defective murine sarcoma virus (SARCOMA VIRUSES, MURINE) capable of transforming mouse lymphoid cells and producing erythroid leukemia after superinfection with murine leukemia viruses (LEUKEMIA VIRUS, MURINE). It has also been found to transform cultured human fibroblasts, rat liver epithelial cells, and rat adrenocortical cells. | |
| Sarcoma Viruses, Murine Mouse Sarcoma Viruses | Murine Sarcoma Viruses | Sarcoma Viruses, Mouse A group of replication-defective viruses, in the genus GAMMARETROVIRUS, which are capable of transforming cells, but which replicate and produce tumors only in the presence of Murine leukemia viruses (LEUKEMIA VIRUS, MURINE). | |
| Genes, abl abl Genes | c-abl Genes | v-abl Genes | abl Oncogene | bcr-abl Proto-Oncogenes | bcr-v-abl Oncogenes | c-abl Proto-Oncogenes | v-abl Oncogenes | Gene, abl | Gene, c-abl | Gene, v-abl | Genes, c-abl | Genes, v-abl | Oncogene, abl | Oncogene, bcr-v-abl Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia. | |
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