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| Adrenal Hyperplasia, Congenital Adrenogenital Syndrome | Congenital Adrenal Hyperplasia | Hyperplasia, Congenital Adrenal | Adrenal Hyperplasias, Congenital | Adrenogenital Syndromes | Congenital Adrenal Hyperplasias | Hyperplasias, Congenital Adrenal A group of syndromes caused by inherited defects in cortisol (HYDROCORTISONE) and/or ALDOSTERONE biosynthesis. There are several types including simple virilizing forms (adrenogenital syndrome), salt-wasting forms, and virilizing hypertension forms depending on the enzyme of defects. Defects in STEROID 21-HYDROXYLASE are most common. Other defects occur in STEROID 11-BETA-HYDROXYLASE, STEROID 17-ALPHA-HYDROXYLASE, or 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES). | |
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