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| Chromosomal Proteins, Non-Histone Non-Histone Chromosomal Proteins | Chromosomal Proteins, Non Histone | Chromosomal Proteins, Nonhistone | Non-Histone Chromosomal Phosphoproteins | PS1 Protein | Chromosomal Phosphoproteins, Non-Histone | Non Histone Chromosomal Proteins Nucleoproteins which in contrast to histones are acid insoluble. They are involved in chromosomal functions; e.g. they bind selectively to DNA, stimulate transcription resulting in tissue-specific RNA synthesis and undergo specific changes in response to various hormones or phytomitogens. | |
| Chromosomes, Human Chromosome, Human | Human Chromosome | Human Chromosomes Very long DNA molecules and associated proteins, HISTONES, and non-histone chromosomal proteins (CHROMOSOMAL PROTEINS, NON-HISTONE). Normally 46 chromosomes, including two sex chromosomes are found in the nucleus of human cells. They carry the hereditary information of the individual. | |
| High Mobility Group Proteins HMG Proteins | Calf Thymus Chromatin Protein HMG | High Mobility Group Chromosomal Proteins A family of low-molecular weight, non-histone proteins found in chromatin. | |
| Chromatin Chromatins The material of CHROMOSOMES. It is a complex of DNA, HISTONES, and nonhistone proteins (CHROMOSOMAL PROTEINS, NON-HISTONE) found within the nucleus of a cell. | |
| Translocation (Genetics) Chromosomal Translocation | Translocation, Chromosomal | Translocation | Chromosomal Translocations | Translocations | Translocations (Genetics) | Translocations, Chromosomal A type of aberration characterized by fragmentation of a chromosome and transfer of the broken-off portion to another chromosome, often of a different pair. | |
| Synteny Chromosomal Colinearity | Colinearity, Chromosomal | Conserved Synteny | Syntenic Conservation | Syntenic Homology | Chromosomal Colinearities | Colinearities, Chromosomal | Conservation, Syntenic | Conservations, Syntenic | Conserved Syntenies The presence of two or more genetic loci on the same chromosome. Extensions of this original definition refer to the similarity in content and organization between chromosomes, of different species for example. | |
| RNA, Nuclear Chromosomal RNA | Nuclear RNA | RNA, Chromosomal RNA molecules found in the nucleus either associated with chromosomes or in the nucleoplasm. | |
| Chromosome Pairing Synapsis | Synapsis, Chromosomal | Chromosomal Synapsis | Chromosome Pairings The alignment of CHROMOSOMES at homologous sequences. | |
| PrPC Proteins Scrapie Amyloid Precursor Protein | Cp 33-35 | Cp33-35, Scrapie | PrP-sen | PrP sen Normal cellular isoform of prion proteins (PRIONS) encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity. | |
| Fusion Proteins, bcr-abl Oncogene Protein p190(bcr-abl) | Oncogene Protein p210(bcr-abl) | bcr-abl Fusion Proteins | Fusion Proteins, bcr abl | Proteins, bcr-abl Fusion | bcr abl Fusion Proteins Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in Abelson murine leukemia virus. | |
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